Stabil idiyopatik pulmoner fibrozde hastalik şiddeti ve prognostik belirteçler ile matriks metallaproteinaz düzeyleri arasindaki ilişki

Purpose: Blood-derived biomarkers have been extensively considered as possible prognostic indicators in idiopathic pulmonary fibrosis (IPF) recently. In order to assess the value of circulating common IPF clinical practice, study intends draw conclusions regarding link between disease severity, indicators, and serum matrix metalloproteinase patients with stable fibrosis.
 Materials Methods: The comprised 22 people an diagnosis that had verified by a multidisciplinary approach. sociodemographic details, radiologic symptoms, function tests Gender-Age-Physiology (GAP) score were noted. ELISA has used research MMP concentrations.
 Results: There is no statistically significant correlation Matrix Metalloproteinase (MMP) 2, 7, 9, MMP13 GAP index and, tests, or severity. was found be higher stage 3 severe disease, 2 moderate 1 mild disease.
 Conclusion: are consistent findings literature, despite fact association markers, severity could not seen this investigation. However, because they open door cutting-edge treatment strategy, these should investigated prospectively larger series.